QUOTE(SharonG @ Jul 25 2006, 09:04 AM)
QUOTE(Dr Evil @ Jul 25 2006, 08:28 AM)
Ibuprofen is pretty benign stuff...
I was told (by a nurse) to take ibuprofen with a lot of water since it's hard on the kidneys... is this not true?
Every drug we take is metabolized in some way. Lungs (breathed out) Kidneys (urination) Liver (processed by cytochrome P450 system or other enzymes) eliminated in urine or bile. Some are even sweated out.
While it is true that Ibuprofen is eliminated by the kidneys, I don't think that is a problem for normal kidneys with normal doses.
This nurse may have had other reasons for wanting you to drink more. Fever, dehydration, history of high blood pressure, etc...
It is always good advice to drink lots of water. Americans in particular tend to drink lots of stuff that causes a net loss in fluid. caffiene containing fluids etc.